Mute the noise

Spotlight the signal with the next-generation Oncodetect MRD test

Dark gray DNA helixes with an orange circle around one gold helix.

What is molecular residual disease?

Molecular residual disease (MRD) can be shed by cancer cells into the bloodstream in the form of tumor-specific DNA, also called circulating tumor DNA or ctDNA. This can happen during or after cancer treatment.

  • The presence of ctDNA may indicate that cancer is present in the body, even when not detected by current standard of care methods.2
  • ctDNA contains unique variants that can be detected by highly sensitive tests, offering real-time measurement of the disease burden.3
  • The detection and monitoring of MRD can help inform treatment decisions.4
A doctor smiling while talking with a patient.

Detect cancer early to inform treatment decisions

The next-generation Oncodetect test looks for minute signs of cancer related to a specific tumor. This kind of MRD testing allows you to detect cancer recurrence or progression earlier than with current standard methods,1,2 as well as monitor the disease over time.

Earlier detection and monitoring can help patients and providers:

  • Determine whether any cancer is detectable post-surgery, or if further treatment is necessary.1
  • Assess whether the cancer is likely to come back.1
  • Learn how cancer is responding to treatment.1
An Exact Sciences employee smiling while standing in a laboratory setting.



Innovation you can trust

We’re dedicated to helping patients and providers make the most informed decisions in cancer prevention, treatment, and monitoring, by harnessing the latest innovations in screening and detection.

With more than 20 years of experience in genomic oncology, we’ve empowered over 2 million patients5 living with cancer through our portfolio of tests. We have invested in the latest MRD technologies and will continue to advance this field for the benefit of the patient and clinician.

With the Oncodetect test, you get highly sensitive ctDNA detection,6 meaningful insights to help make timely treatment decisions, and customer support that’s here for you every step along the way.

The limit of detection of the next-generation Oncodetect test is 30x lower than our first-generation test.6,7

With an ultra-low limit of detection, the next-generation Oncodetect test provides residual disease detection and monitoring, allowing you to make more informed treatment decisions.

Outstanding sensitivity, high specificity.6

By tracking up to 5,000 variants specific to a patient’s tumor, the next-generation Oncodetect MRD test grants more opportunities to detect ctDNA in the blood compared to the first-generation test.6,7 With a high level of sensitivity and >99% analytical specificity,6 it can help providers and patients assess whether cancer is remaining in the body, recurring, or is responding to specific treatment.

5,000

The next-generation Oncodetect test tracks up to 5,000 tumor-specific variants, leveraging broad coverage to achieve an ultra-low limit of detection.1

1,000x

The next-generation Oncodetect test can enrich tumor DNA up to 1000x, making ultra-rare mutations easy to detect with greater confidence compared to the first-generation Oncodetect test.1.9

<1ppm*

An ultra-low limit of detection provides confidence when every molecular signal counts.8

*Under high-end inputs.

Have questions?

Call us at +1 866-662-6897.